CORTISONE : CORTISOL RATIO
Children with Hypoadrenalism exhibit a greater decrease in cortisol as compared with cortisone. Usually in these cases cortisone levels are higher than cortisol levels and the cortisone / cortisol ratio exceeds 1.0. Children with adrenal cancer exhibit normal or high values of cortisol, whereas cortisone levels are decreased and the cortisone / cortisol ratio is nearly zero. The ratio becomes normal after excision of adrenal tumors.
Diurnal variation present; take sample between 8-10 am OR 4-6 pm.
Sample Daily by 4 pm; Report 2 days