DPYD (DEOXYPYRIDINOLINE), URINE
DPYD is formed during collagen maturation in bone and is released during bone resorption. Approximately 40% is found free in urinary excretions and 60% is bound to small peptides. DPYD Free is a sensitive and specific marker of bone resorption.
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Pre-test Information:
First morning urine sample recommended. Wrap the container in aluminium foil / dark paper. If used for monitoring therapy , urine should be collected at the same time on each occasion as for the baseline specimen.
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Report Delivery:
Sample by Mon 4 pm; Report Same day
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Scl-70 (SCLERODERMA) ANTIBODY
Scl-70 antibodies are considered to be specific for Scleroderma and are found in nearly 60% of these patients. They are more common in patients with extensive cutaneous involvement and Interstitial pulmonary fibrosis and their presence is a poor prognostic indicator.
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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SS-B/La ANTIBODY
SS-B/La is an extractable nuclear antigen with antibodies occuring in patients with Sjogren’s syndrome (60%) & Lupus erythematosus (15%). This assay is useful for evaluating patients with signs and symptoms of connective tissue disorder in whom ANA is positive.
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Pre-test Information:
Overnight fasting is preferred
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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SS-A/Ro ANTIBODY