Bone is a dynamic tissue that is remodelled constantly throughout life. It provides a reservoir for calcium, phosphorus, and other ions for homeostatic functions. Several genetic and acquired diseases cause tubular phosphate wasting with Rickets and Osteomalacia. Renal phosphate wasting may be accompanied by low levels of Vitamin D & calcium with evidence of impaired cartilage or bone mineralization.
Collect fasting sample between 8–10 a.m. Avoid use of tourniquet and fist clenching during sampling.