PCNA (PROLIFERATING CELL NUCLEAR ANTIGEN), ANTIBODY

ANA is useful in the diagnosis of patients with autoimmune diseases such as SLE, Mixed connective tissue disease, Rheumatoid arthritis, Sjogren’s syndrome, Progressive systemic sclerosis and CREST syndrome. The incidence of low titre ANA positivity increases with age in normal individuals. many drugs like Hydralazine and Procainamide may induce ANA production.