PCNA (PROLIFERATING CELL NUCLEAR ANTIGEN), ANTIBODY
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Scl-70 (SCLERODERMA) ANTIBODY
Scl-70 antibodies are considered to be specific for Scleroderma and are found in nearly 60% of these patients. They are more common in patients with extensive cutaneous involvement and Interstitial pulmonary fibrosis and their presence is a poor prognostic indicator.
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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U1RNP ANTIBODIES
U1RNP antibody in combination with Smith antibody provides additional support for the diagnosis of SLE. A positive U1RNP antibody alone with the corresponding clinical history supports the diagnosis of Mixed connective tissue disease.
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Pre-test Information:
Overnight fasting is preferred
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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Jo-1 ANTIBODY
Jo-1 antibodies are a marker of Polymyositis & occur most commonly in Myositis patients who also have Interstitial lung disease. The antibodies are detected in 50% patients with Interstitial pulmonary fibrosis & Symmetrical polyarthritis
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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