Scl-70 (SCLERODERMA) ANTIBODY
Scl-70 antibodies are considered to be specific for Scleroderma and are found in nearly 60% of these patients. They are more common in patients with extensive cutaneous involvement and Interstitial pulmonary fibrosis and their presence is a poor prognostic indicator.
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
Related Products
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SJOGREN’S SYNDROME ANTIBODIES
SSA/Ro & SSB/La are extractable nuclear antigens. SS-A/Ro antibodies occur in patients with Sjogren’s syndrome (90%), Lupus erythematosus (40-60%) & Rheumatoid arthritis. SS-B/La antibodies occur in patients with Sjogren’s syndrome (60%) &Lupus erythematosus (15%). This assay is useful for evaluating patients with signs and symptoms of connective tissue disorder in whom ANA is positive.
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Test Type:
Blood
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same Day
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Components:
2
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Sm (SMITH) ANTIBODY, IgG
Smith antibodies are specific for Lupus erythematosus occuring in nearly 30%of these patients. It is a component of extractable nuclear antigens also seen in other connective tissue disorders. This assay is useful for evaluating patients with signs and symptoms of a connective tissue disorder in whom ANA is positive.
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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CENTROMERE ANTIBODY
Centromere antibodies occur primarily in patients with CREST syndrome but may also be seen in some patients with Primary biliary cirrhosis, Rheumatoid arthritis and LE. This assay is used as an aid in the diagnosis of CREST syndrome and for evaluating patients with clinical presentation compatible with Systemic sclerosis.
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Pre-test Information:
Overnight fasting is preferred
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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Jo-1 ANTIBODY
Jo-1 antibodies are a marker of Polymyositis & occur most commonly in Myositis patients who also have Interstitial lung disease. The antibodies are detected in 50% patients with Interstitial pulmonary fibrosis & Symmetrical polyarthritis
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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