Scl-70 (SCLERODERMA) ANTIBODY
Scl-70 antibodies are considered to be specific for Scleroderma and are found in nearly 60% of these patients. They are more common in patients with extensive cutaneous involvement and Interstitial pulmonary fibrosis and their presence is a poor prognostic indicator.
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
Related Products
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Jo-1 ANTIBODY
Jo-1 antibodies are a marker of Polymyositis & occur most commonly in Myositis patients who also have Interstitial lung disease. The antibodies are detected in 50% patients with Interstitial pulmonary fibrosis & Symmetrical polyarthritis
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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ANTI NUCLEAR ANTIBODY / FACTOR (ANA/ANF), EIA
ANA is useful in the diagnosis of patients with autoimmune diseases such as SLE, Mixed connective tissue disease, Rheumatoid arthritis, Sjogren’s syndrome, Progressive systemic sclerosis and CREST syndrome. The incidence of low titre ANA positivity increases with age in normal individuals. many drugs like Hydralazine and Procainamide may induce ANA production.
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Test Type:
Blood
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Pre-test Information:
Overnight fasting is preferred
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Report Delivery:
Sample Daily by 9 am; Report Same day
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HLA-B27, FLOW CYTOMETRY
HLA B 27 positivity is associated with Ankylosing spondylosis and other diseases like Reiter’s syndrome, Anterior uveitis, Salmonella/Yersinia/ Psoriatic/ Juvenile Chronic Arthritis, Spondylitis with Inflammatory Bowel Disease.
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Test Type:
Blood
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample Daily by 9 am; Report Same day
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Sm (SMITH) ANTIBODY, IgG
Smith antibodies are specific for Lupus erythematosus occuring in nearly 30%of these patients. It is a component of extractable nuclear antigens also seen in other connective tissue disorders. This assay is useful for evaluating patients with signs and symptoms of a connective tissue disorder in whom ANA is positive.
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Pre-test Information:
No special preparation required
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Report Delivery:
Sample by Tue / Fri 9 am; Report Same day
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